(#8389) Gpr139, a Modulator of Mu Opioid Receptor, is a Target of Sonic Hedgehog Signaling in Cholinergic Interneurons of the Adult Striatum and Modulates Cholinergic Activity

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(#8389) Gpr139, a Modulator of Mu Opioid Receptor, is a Target of Sonic Hedgehog Signaling in Cholinergic Interneurons of the Adult Striatum and Modulates Cholinergic Activity Neuroscience, 2021 (SFN) Dustin R. Zuelke, Sonia Bernal, Aria Walls, and Andreas H. Kottmann … Read More

(#7156) Sonic Hedgehog Signaling onto Striatal Cholinergic Interneurons Impinges on D2 Signaling via the Integrated Stress Response Pathway to Mediate L-dopa Induced Dyskinesia Induction

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(#7156) Sonic Hedgehog Signaling onto Striatal Cholinergic Interneurons Impinges on D2 Signaling via the Integrated Stress Response Pathway to Mediate L-dopa Induced Dyskinesia Induction Neuroscience, 2021 (SFN) Santiago Uribe-Cano, Kalena Liu, Michael Holmes, Lauren Malave, and Andreas H. Kottmann Dopamine … Read More

(P109.02) Identification of GPR139 as an attenuator of LID through striatal interneuron transcriptional profiling

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(P109.02) Identification of GPR139 as an attenuator of LID through striatal interneuron transcriptional profiling Society for Neuroscience Global Connectome, 2021 Dustin R. Zuelke, Katelyn Kennedy, Patrick Barkaus, and Andreas H. Kottmann Cholinergic interneurons (CINs) of the striatum have been recognized … Read More

Current Abstracts

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                        Neuroscience 2021 (SFN) (#7156) Sonic Hedgehog Signaling onto Striatal Cholinergic Interneurons Impinges on D2 Signaling via the Integrated Stress Response Pathway to Mediate L-dopa Induced Dyskinesia Induction (#8389) Gpr139, … Read More

Preprints

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  “Multiple sources of Shh are critical for the generation and scaling of ventral spinal cord oligodendrocyte precursor populations”. (2021) bioRxiv Lev Starikov, Miruna Ghinia-Tegla, and Andreas H. Kottmann ______________________________________________________________

Join our team

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Post-doctoral Fellow Positions Please contact Andreas Kottmann directly: Phone: (212) 650-8644 Email: akottmann@med.cuny.edu Graduate Students The Kottmann Lab is a member lab of the CUNY graduate programs in Molecular, Cellular, and Developmental Biology and Neuroscience as well as the CUNY … Read More

Publications

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“Dopaminergic Co-transmission With Sonic Hedgehog Inhibits Abnormal Involuntary Movements in Models of Parkinson’s Disease and L-Dopa Induced Dyskinesia”. (2021) Communications Biology 2021 Malave, Lauren, Dustin R. Zuelke, Santiago Uribe-Cano, Lev Starikov, Heike Rebholz, Eitan Friedman, Chuan Qin, Qin Li, Erwan … Read More